WebAU - Cuppen, Edwin. AU - Snippert, Hugo J. AU - Medema, Jan Paul. AU - Kops, Geert J P L. AU - Clevers, Hans. PY - 2015/5/7. Y1 - 2015/5/7. N2 - Crypt stem cells represent the … WebEdwin Cuppen is initiator and scientific director of the Hartwig Medical Foundation (part-time since 2015 and full time since 2024), a not-for-profit organisation that aims to …
Chromothripsis as a mechanism driving complex de novo …
WebWienholds, E., van Eeden, F., Kosters, M., Mudde, J., Plasterk, R.H., and Cuppen, E. (2003) Efficient target-selected mutagenesis in zebrafish. Genome research. 13:2700-2707 Wienholds, E., Koudijs, M.J., van Eeden, F.J., Cuppen, E., and Plasterk, R.H. (2003) The microRNA-producing enzyme Dicer1 is essential for zebrafish development. WebJul 1, 2024 · Whole genome sequencing (WGS) using fresh-frozen tissue and matched blood samples from cancer patients may become the most complete genetic tumor test. … ira\u0027s that invest in crypto
Unscrambling cancer genomes via integrated analysis of structural ...
WebMar 22, 2024 · Edwin Cuppen. Edwin Cuppen. Affiliations. Hartwig Medical Foundation, Science Park 408, Amsterdam, the Netherlands. Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, the Netherlands. Search for articles by this author. WebNov 4, 2024 · Here, we develop a genome-wide mutational scar-based pan-cancer Classifier of HOmologous Recombination Deficiency (CHORD) that can discriminate BRCA1- and BRCA2-subtypes. Analysis of a metastatic (n = 3,504) and primary (n = 1,854) pan-cancer cohort reveals that HRD is most frequent in ovarian and breast cancer, followed by … WebEdwin CUPPEN, Research Director Cited by 32,004 Read 623 publications Contact Edwin CUPPEN orchitis treatment cks