WebJul 5, 2024 · Bioassay results showed that six of them (1–4, 6 and 7), with the exception of 5, produce some cytotoxicity on RAW264.7 cells at its high dosage, can significantly decrease the release of NO, TNF-α, IL-1 β, IL-6 and PGE2 in a dose dependent manner, and down-regulate the expression of proteins iNOS and COX-2. WebDec 1, 2024 · The glycyrrhetinic acid was highly effective in down-regulating iNOS activity. Abstract. Glycyrrhizae Radix et Rhizoma, a traditional Chinese medicine also known as Gan Cao (GC), is frequently included in clinical prescriptions for the treatment of pneumonia. However, the pharmacological components of GC for pneumonia treatment are rarely …
Regulation of inducible nitric oxide synthase by rapid …
WebApr 4, 2024 · Rutin coated gold nanoparticles prevent rhabdomyolysis-induced kidney injury via down-regulation of NF-kB, iNOS, IL-6 and up-regulation of HO-1 and Kim-1 genes in mice. iNOS/NO is required for IRF1 activation in response to liver ischemia-reperfusion in mice. Nicorandil mitigates folic acid-induced nephrotoxicity in mice: Role of iNOS and … WebAug 9, 2014 · ASA reduces iNOS expression by downregulating promoter activity, mRNA and protein levels at the same time that it decreases HCV expression. These findings suggest that the antiviral activity of... products for vaginal dryness after menopause
Menstrual blood-derived endometrial stem cells alleviate ...
WebApr 13, 2024 · Neuroinflammation is closely related to the development of Parkinson's disease (PD). Because of the extensive sources, non-invasive and periodical collection method, human menstrual blood-derived endometrial stem cells (MenSCs) have been explored as a promising tool for treatment of PD. This study aimed to investigate if … WebThe expression of the inducible nitric oxide synthase (iNOS) is one of the direct consequences of an inflammatory process. Early studies have focused on the potential toxicity of the ensuing high-output NO-synthesis serving as a means to eliminate pathogens or tumor cells but also contributing to local tissue destruction during chronic inflammation. WebFeb 1, 2024 · ( Luo 2008) Administration of a mixture of nobiletin and its major metabolites for 19 weeks to mice with colitis-associated colon carcinogenesis resulted in a decrease in cell cycle progression in the colon tissue, which was at least partially related to downregulation of iNOS. release first dorsal compartment left wrist