Web6) Shown here are data from the Hollopeter lab. In this experiment, they tested the ability of fluorescently labeled adaptin proteins to appear at the surface of cells using fluorescent recovery after photobleaching (FRAP) in worms (C. elegans): 1) expressing WT FCHo protein (fcho(+)) or 2) expressing NO FCHo protein (fcho(-)) or 3) expressing a FCHo … WebJan 19, 2024 · The pioneering endocytic protein FCHo2 promotes clathrin-coated structures assembly via the formation of phosphoinositide-enriched domains at the boundary of cargo receptors. ... (Figure 1F), that in supported bilayers, PIP4,5P2 recruits FCHo. It is also expected that FCHo punctae would have a longer, more stable association with …
Human FCHO1 deficiency reveals role for clathrin-mediated
WebIt was recently shown that variations in the ratio of dietary fermentable carbohydrates (fCHO) and fermentable protein (fCP) differentially affect large intestinal microbial … WebAug 1, 2011 · FCHo1/2 proteins are key endocytic initiators of clathrin-mediated endocytosis (CME) and contain a membranetubulating extended FCH/FCH and BAR domain (EFC/F-BAR) and a C-terminal μHD, which... tec1-12705t125
Entry - *613438 - FCH DOMAIN ONLY PROTEIN 2; FCHO2 - OMIM
WebOct 25, 2024 · Over the past few decades, Chinese hamster ovary (CHO) cells represent the most commonly used production cell line for therapeutic proteins [ 2 ]. We previously engineered a stable site-specific-integrated cell line, Flp-In TM CHO/IL-24 (FCHO/IL-24), to express recombinant human IL-24 (rhIL-24) using the Flp-In system. WebPubMed WebOct 10, 2014 · The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex. The AP2 clathrin adaptor complex links protein … tec1 12706 thermoelectric peltier cooler