Plectin网蛋白

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August undefined, 2024

Webbplectin in Chinese : 网蛋白…. click for more detailed Chinese translation, meaning, pronunciation and example sentences.

Plectine — Wikipédia

WebbPlectin expression is linked to poor disease prognosis in pancreatic, as well as in lung cancer, where it has been identiﬁed as a biomarker for lung cancer stem cells [23]. WebbPlectin antibody detects Plectin protein at cytoskeleton by immunofluorescent analysis. Sample: U2OS cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Plectin stained by Plectin antibody (GTX130764) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at … ranger boat models by year

plectin in Chinese - plectin meaning in Chinese - plectin Chinese …

Webb14 okt. 2008 · Description. A form of epidermolysis bullosa, a genodermatosis characterized by recurrent blistering, fragility of the skin and mucosal epithelia, and erosions caused by minor mechanical trauma. EBS5C is an autosomal recessive disorder characterized by severe skin blistering at birth and congenital pyloric atresia. Death … Webb4 apr. 2024 · plectin, hemidesmosomal protein 1, plectin 1, intermediate filament binding protein 500kDa GeneRIFs: Gene References Into Functions Plectin Downregulation … Webb1 okt. 1996 · In this context, it was of interest that markedly reduced or absent expression of plectin within the skin was associated with reduced staining for the 230 kDa bullous pemphigoid antigen, suggesting that the pathology of the skin may be, at least in part, a reflection of the reduction of this protein, or that plectin and the 230 kDa bullous … owens corning proedge ar hip \\u0026 ridge

PLEC protein expression summary - The Human Protein Atlas

Homozygous Deletion Mutations in the Plectin Gene (PLEC1) in …

Webb1 jan. 2015 · 中文摘要. 分子影像使活体、早期发现肿瘤癌变过程中的分子异常成为可能。. 研究发现Plectin-1在胰腺癌及转移灶中高表达，在正常胰腺中不表达，表明Plectin-1与胰腺癌关系密切。. 本项目选择Plectin-1为成像靶点，首先构建荧光、纳米粒双模态靶向探针，采 … WebbPlectin is a large, widely expressed protein that crosslinks the intermediate filament and actin cytoskeleton, mechanically stabilizing cells and tissues. Plectin also plays a role in … owens corning pro armorWebb除原位胰腺组织外，Plectin-1在转移性病变包括肝脏、淋巴结和腹膜组织的免疫组化研究中均有显着表达。通过上述研究说明，Plectin-1的表达特点和表达量可用于鉴别胰腺的良恶性病变，可成为特殊的生物标记。 owens corning proedge ar 33\\u0027 - driftwood

"WebbPlektin (engl.Plectin, kurz PCN oder PLTN), auch Plectin-1 oder Hemidesmosomal protein 1 (HD1), ist ein bei Eukaryoten vorkommendes Protein.Es lässt sich im Zytoplasma nahezu aller eukaryotischen Zellen nachweisen, in großen Mengen jedoch vor allem in Muskel- und Herzmuskelzellen, Hautzellen, Nervenzellen sowie in Zellen der Plazenta. . Plektin ist ein … " - Plectin网蛋白

Plectin网蛋白

WebbAll lanes : Anti-Plectin antibody [E398P] (ab32528) at 1/5000 dilution Lane 1 : Wild-type U-2 OS cell lysate Lane 2 : PLEC knockout U-2 OS cell lysate Lysates/proteins at 20 µg per lane. Performed under reducing conditions. Predicted band size: 532 kDa ab32528 was shown to react with PLEC in wild-type U-2 OS cells in Western blot with loss of signal observed in a … Webb15 sep. 2013 · Plectin is a versatile cytolinker of the plakin family conferring cell resilience to mechanical stress in stratified epithelia and muscles. It acts as a critical organizer of the cytoskeletal system by tethering various intermediate filament (IF) networks through its C-terminal IF-binding domain (IF …

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Webb21 mars 2024 · PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex 5A, Ogna Type and Muscular Dystrophy, Limb … Webbplectin expression or by expressing only rodless plectin variants, as demonstrated in EBS-MD skeletal muscles [22]. Plectin mutations in EBS-MD patients and their links on CNS abnormalities are described below in the chapter Plectin-related Pathologies of the Central Nervous System. 2. Plectin in the Central Nervous System

Webb病理结果：苏木精-伊红染色可见核链，肌核聚集；抗-plectin免疫组织化学染色可见plectin蛋白在肌浆中聚集。 PLEC基因突变所致的肢带型肌营养不良2Q型报道较少，本研究新发1例因 PLEC 基因c.6428C>T和c.13192G>A复合杂合错义突变所致的肢带型肌营养不良2Q型，扩展了 PLEC 基因的突变谱，也加深临床医师对该 ... Webb12 nov. 2024 · 经蛋白组学分析，靶向肽PTP是通过与胰腺癌发生时误定位在细胞膜表面上的plectin-1特异性结合实现靶向作用的。然而，胰腺癌在遗传上是非常复杂的，肿瘤的质量是由患者的63个基因改变和12个核心信号通路的异常引起的，在不同癌症患者的肿瘤生物标志物表达中存在异质性。

Webb31 juli 2024 · Abstract. Plectin, a high-molecular-weight cytoskeletal linker protein, binds with high affinity to intermediate filaments of all types and connects them to junctional complexes, organelles, and inner membrane systems. In addition, it interacts with actomyosin structures and microtubules. Webb16 apr. 2014 · Tissue specificity. Detected in eye lens fiber cells (at protein level) ( PubMed: 21745462 ). Expressed at high levels in lung, brain, small intestine, muscle, heart and skin with lower levels found in kidney, liver, uterus, spleen and salivary gland ( PubMed: 10556294 ). 2 publications.

Webb20 nov. 2024 · As plectin is a critical regulator for cell cytoarchitecture and motility, we next measured the effects of plectin knock-down on prostate cancer invasion and migration.

Webb15 apr. 2008 · As an in vivo screening approach, we have used phage as targeted nanoparticles for imaging by labeling the phage coat proteins with a near infrared fluorochrome [ 21, 27 ]. The Cy5.5-labeled phage were injected IV 4 h prior to imaging for both the distribution and tumor imaging studies. ranger boat seats benchWebb30 apr. 1996 · Plectin, a 500-kDa intermediate filament binding protein, has been proposed to provide mechanical strength to cells and tissues by acting as a cross-linking element … owens corning proedge hip and ridge shinglesWebb网蛋白（plectin）是半桥粒组成成分中分子量最大的一种，约500kD，和BPAG1同处于半桥粒的细胞内侧，位于半桥粒内斑块的细胞最内缘，比BPAG1位置略高。网蛋白对多种蛋 … owens corning proedge ar 33\u0027 - driftwoodhttp://fund.keyanzhiku.com/Index/info/id/OTEwMDIxMTUwYmllLXNoaS1sZS1xdS1iaWUtcmVuLWppYS1wYS1zaHUtanUtYmE%3D.html ranger boat livewell pumpWebb30 aug. 2024 · Plectin has been widely leveraged to enhance the specificity of imaging agents and the efficacy of therapeutic modalities. Plectin-targeting peptides (PTPs) or … owens corning proarmorWebbPlectin-1 Antibody 可检测内源水平的总网蛋白-1。根据免疫原性肽的序列，该抗体预计会与网蛋白-1 的所有同工型发生交叉反应。物种反应性：人, 猴来源/纯化使用与人网蛋 … ranger boats for sale in wisconsinWebbplectin, a cytolinker protein that mislocalized onto the cell surface during malignant transformation of healthy ovarian tissue. This cancer specific phenotype allowed us to image pancreatic cancer successfully using plectin targeted peptide (PTP) conjugated to nanoparticles or displayed on capsid protein of adeno-associated virus (AAV) particles. ranger boats clothing apparel