Sialophorin
WebGene "Gene description" Evidence A1CF "APOBEC1 complementation factor" "Evidence at protein level" A4GALT "Alpha 1,4-galactosyltransferase (P blood group)" "Evidence at protein le WebAll-trans retinoic acid (ATRA) and valproic acid (VP) have been tried in the treatment of non-promyelocytic variants of acute myeloid leukemia (AML). Non-randomized studies suggest that the two drugs can stabilize AML and improve normal peripheral blood cell counts. In this context, we used a proteomic/phosphoproteomic strategy to investigate the in vivo …
Sialophorin
Did you know?
WebApr 11, 2024 · CD43, also known as Leukosialin and Sialophorin and Ly-48 in mouse, is a 100-105 kDa type I transmembrane sialylated mucin that is expressed on most leukocytes and some tumor cells. Notably, the membrane expression of CD43 seems to be a characteristic of leukocytes, while cytoplasmic expression without membrane Sialophorin (leukosialin) is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which appears to be important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. See more Leukosialin also known as sialophorin or CD43 (cluster of differentiation 43) is a transmembrane cell surface protein that in humans is encoded by the SPN (sialophorin) gene. See more Defects in the CD43 molecule are associated with the development of Wiskott–Aldrich syndrome. It also appears in about 25% of intestinal MALTomas. Using immunohistochemistry, CD43 can be demonstrated in the paracortical T-cells of healthy lymph nodes … See more • CD43+antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human SPN genome location and SPN gene … See more CD43 has been shown to interact with EZR and Moesin. See more • Fukuda M, Carlsson SR (1987). "Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens". Med. Biol. 64 (6): 335–43. PMID 2950285 See more
WebMay 1, 2024 · Abstract. Increased opportunistic fungal infections in immunocompromised patients and lack of effective therapeutic modalities caused millions of deaths worldwi WebCD43, also known as Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein, and W3/13, is a large single chain, type I transmembrane glycoprotein with abundant O-glycosylation …
WebMar 21, 2024 · SPN (Sialophorin) is a Protein Coding gene. Diseases associated with SPN include Wiskott-Aldrich Syndrome and Aleukemic Monocytic Leukemia Cutis.Among its … Webanti-SPN Monoclonal Antibody reacting with Mouse and identified with ELISA, IHC. Quality is guaranteed.
WebAbstract: Wiskott–Aldrich syndrome (WAS) is an uncommon X-linked combined-immunodeficiency disorder characterized by a triad of thrombocytopenia, eczema, and immunodeficiency. Patients with WAS are also predisposed to autoimmunity and malignancy. Autoimmune manifestations have been reported in 26%– 72% of patients …
http://pruebas.ibt.unam.mx/publicaciones/2024/ dat hot shot load boardWebCD43 (cluster of differentiation 43), also known as leukosialin or sialophorin, is a transmembrane type I glycoprotein being expressed by most human leukocytes, including … björn borg cross shortsWebCD43, also known as leukosialin, galactoglycoprotein, and sialophorin, is a transmembrane cell surface protein. It has both adhesive and anti-adhesive functions. björn borg court duffelWebThe U.S. Department of Energy's Office of Scientific and Technical Information bjorn borg countryWebOct 1, 1994 · Sialophorin (CD43) is a major surface mucin on most hematopoietic cell lineages, including phagocytes. Defects of CD43 expression occur in Wiskott-Aldrich … bjorn borg essentialWebEffective stimulation was dependent on the presence of monocytes and the Fc portion of L10 mAb. Stimulation of lymphocytes by L10, like stimulation by anti-CD3 mAb, involves … dathreaWebMay 1, 1987 · Europe PMC is an archive of life sciences journal literature. The mAb L10 was used to determine the distribution and the function of sialophorin, the heavily glycosylated … björn borg country sports