Solifenacin, sold as the brand name Vesicare among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). It may help with incontinence, urinary frequency, and urinary urgency. Benefits appear similar to other medications in the class. It is taken by mouth. Common side … See more It is used to treat overactive bladder. It may help with incontinence, urinary frequency, and urinary urgency. Benefits appear similar to other antimuscarinics such as oxybutynin, tolterodine, … See more The most common side effects of solifenacin are dry mouth, constipation and urinary tract infection. As all anticholinergics, … See more Mechanism of action Solifenacin is a competitive cholinergic receptor antagonist, selective for the M3 receptor subtype. The binding of acetylcholine to these receptors, particularly M3, plays a critical role in the contraction of See more The compound was studied using animal models by the Yamanouchi Pharmaceutical Co., Ltd. of Tokyo, Japan. It was known as YM905 when under study in the early 2000s. See more Solifenacin is contraindicated for people with urinary retention, gastric retention, uncontrolled or poorly controlled closed-angle glaucoma, severe liver disease (Child-Pugh class … See more Solifenacin is metabolized in the liver by the cytochrome P450 enzyme CYP3A4. When administered concomitantly with drugs that See more Like other anticholinergics, solifenacin is an ester of a carboxylic acid containing (at least) an aromatic ring with an alcohol containing a … See more WebSolifenacin is used to treat an overactive bladder. By relaxing the muscles in the bladder, solifenacin improves your ability to control your urination. It helps to reduce leaking of …
Solifenacin: MedlinePlus Drug Information
WebNov 23, 2009 · AUCss of Solifenacin [ Time Frame: Week 4, Week 8 and Week 12 (collection time points: trough, 1-3 hours post dose, 4-5 hours post-dose and 7-10 hours post-dose) ] Eligibility Criteria. Go to Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information. WebAug 26, 2011 · Null hypothesis of the trial is that there is no difference between solifenacin and oxybutynin with respect to efficacy, side effects, patient satisfaction and quality of life measures in patients with overactive bladder. Condition or … portal 2 show fps
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WebSolifenacin may interact with a few medications and herbal supplements, so check with your doctor or pharmacist. Solifenacin may also interact with some medicines available over-the-counter, without a prescription such as some antihistamines (also in anti-allergy, anti-nausea and cough/cold preparations), meclozine (e.g. Sea-legs®), prochlorperazine (e.g. … WebFeb 18, 2024 · Solifenacin có thể tương tác với các thuốc như pramlintide, viên nén/viên nang kali. Các loại thuốc khác có thể ảnh hưởng đến việc loại bỏ solifenacin khỏi cơ thể của bạn, điều này có thể ảnh hưởng đến cách solifenacin hoạt động. Các thuốc này bao gồm một số thuốc ... WebSep 30, 2024 · Solifenacin is used to treat a condition called overactive bladder. Overactive bladder happens when you cannot control your bladder muscle. When the muscle contracts too often or cannot be controlled, you get symptoms of overactive bladder such as: not being able to control when to empty your bladder, where you get a strong need to urinate … irsa-imagerie.com rochefort